Yes, Booker, a beautiful area of France. Admittedly, my wife and I and our daughter and her boyfriend were there for only a few days. We were attending my wife's niece's wedding about 15 miles northwest of Avignon (at an old winery) and it was one of those 3-day, "destination weddings", so we didn't have a huge amount of extra time to sightsee. But Avignon is a beautiful, medieval city - definitely worth spending a day or part of day exploring and there are several other similar small cities or towns in that area that you should visit. Many wineries and vineyards too - I understand the area is well known for its rose wines (not really my favorite). I'm not sure what the weather is like in March but I assume fairly mild - it's quite far south in France.
We flew to Paris and then took the high-speed train to Avignon - about a 3.5 hour train trip and very nice scenery for most of the train ride.
Are you planning to also ski on the trip? I know it is not that far to the southern French Alps from that area.